Yajun Liu, Junying Zhang, Aimin Li, Zhaowen Liu, Zhongzhen He, Xiguo Yuan, Shouheng Tuo
piwi-interacting RNAs (piRNAs) are valuable biomarkers, but functional studies are still very limited. Recent research shows that piRNA-mediated cleavage acts on Transposable Elements (TEs), messenger RNAs (mRNAs), and long non-coding RNAs (lncRNAs). This study aimed to predict cancer-associated piRNA-mRNA and piRNA-lncRNA interactions as well as piRNA regulatory functions. Four cancer types (BRCA, HNSC, KIRC, and LUAD) were investigated. Interactions were identified by integrated analysis of...