Academic journals are regarded as a microcosm of the times, reflecting the current situation and ideal pursuit of the country and the nation. In a specific era, academic journals inevitably shoulder distinctive missions and tasks. The construction of China's independent knowledge system is a sacred and glorious mission of the scientific community, including academic journals. Based on the discussion closely related to the construction of China's independent knowledge system in the new era, this paper systematically and globally elaborates on the issues related to academic journals serving the construction of China's independent knowledge system. It progressively sorts out the interrelated node issues in "Academic Journals Serving the Construction of China's Independent Knowledge System", such as "What is Academic Journals Serving the Construction of China's Independent Knowledge System? Why Academic Journals Should Serve the Construction of China's Independent Knowledge System? What Standards Should be Used to Achieve Academic Journals Serving the Construction of China's Independent Knowledge System? and How to Achieve Academic Journals Serving the Construction of China's Independent Knowledge System?" This paper progressively clarifies the profound meaning, inevitability, principles, and paths for academic journals to serve the construction of China's independent knowledge system. Starting from the development requirements of the new era, it delves into important issues for academic journals to serve the construction of China's independent knowledge system, and to anchor the possibility and scientific accuracy of academic journals in the construction of China's independent knowledge system. Academic journals are important platforms and carriers for the construction of China's independent knowledge system, and are academic highlands and important participants in promoting the construction of China's independent knowledge system. It is reasonable and feasible to leverage the construction of China's independent knowledge system with academic journals as an important focus and support point.Academic journals should strengthen their sense of mission, responsibility, and urgency, rely on their publications, clarify what they should do, practice what they can do, and contribute their talents and abilities to the construction of China's independent knowledge system in a targeted manner, playing their due role.This has profound significance for academic journals to continuously produce high-quality outcomes that adhere to the correct direction, represent national standards, highlight innovation and creation, and serve practical needs. With the assistance of academic journals, the successful construction of China's independent knowledge system is just around the corner. This system will, in turn, positively influence academic journals, promoting their high-quality and sustainable development. Therefore, in order to avoid neglecting one aspect at the expense of the other, the development of both should receive attention from the academic community and the whole society, so that the function of academic journals in serving the construction of China's independent knowledge system can be fully utilized, and the positive feedback of China's independent knowledge system construction on academic journals should be laid in advance, so that the two complement each other and work together.